Research Scientist- Enzymologist
Lilly
Madrid, ES
hace 1 día
source : DirectEmployers Association

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana.

Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism.

We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Job description The Discovery Chemistry & Technologies organization within Lilly Research Laboratories is seeking a highly skilled scientist to join the Quantitative Biology (QB) Department based in Alcobendas, Madrid.

Molecular and cell pharmacology within Eli Lilly is a core function within Discovery Chemistry Research and Technologies.

Our department provides deep target platform expertise and quality data to advance the science of our drug discovery programs from Hit identification to Candidate Selection.

The candidate will be a key member of the group and provide support and expertise to Oncology programs from target validation to clinical candidate.

Principal responsibilities of the Position : + Design and perform assays to identify the mechanism of action of ligands, including : + Determination of inhibition modality for reversible inhibitors.

  • Characterization of association and dissociation rate constants for enzyme inhibitors.+ Determination of reversibility for Enzyme-Inhibitor interactions.
  • Kinetic evaluation of irreversible compounds.+ Support the implementation of new assay technologies.+ Generation of experimental SOPs and compliance with guidelines for experimental documentation+ Present scientific data in support of research projects.
  • Actively engaged in advancing small molecule drug discovery oncology programs.+ This is a "hands-on" laboratory based position.
  • Basic Qualifications + Ph.D. in cell biology, biochemistry or enzymology / biochemistry+ Postdoctoral studies or at least 2 years of research experience in a biotech / pharma or academia groups+ Extensive knowledge in mechanistic enzymology, enzyme characterization, enzyme kinetics, and protein biochemistry and biophysics.

  • Strong capability to collaborate with scientist in multiple disciplines+ Fluent in English+ Availability to travel (15%) Additional Skills / Preferences + Experience in method development for cell based assays+ Experience with the use of high throughput laboratory automation, including acoustic dispensing and 384 / 96 liquid handlersEli Lilly and Company, Lilly USA, LLC and our wholly owned subsidiaries (collectively "Lilly") are committed to help individuals with disabilities to participate in the workforce and ensure equal opportunity to compete for jobs.
  • If you require an accommodation to submit a resume for positions at Lilly, please email Lilly Human Resources ( Lilly Recruiting Compliance lists.

    lilly.com ) for further assistance. Please note This email address is intended for use only to request an accommodation as part of the application process.

    Any other correspondence will not receive a response.Lilly does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

    At Lilly we strive to ensure our employees are part of a team that cares about them and our shared purpose of making life better for those around the world.

    How do we do this? We continue to look for ways to include, innovate, accelerate and deliver while maintaining integrity, excellence and respect for people.

    We hope that you seek to join us on our journey as we create medicine and deliver improved outcomes for patients across the globe! #WeAreLilly

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