Proteomic expert
Curaxys
Cádiz, España
hace 27 días

Proteomic expert

Curaxys (www.curaxys.com) is a technology based company specialised in the research, development, manufacturing and marketing of monoclonal antibodies (Mab mAb).

Curaxys is currently considered to be the most important biopharmaceutical business project in Spain. The company is committed to achieve an ideal environment for the professional development of its employees, as well as common personal and business goals.

Job description

The position involves the management of all activities related to the structural characterisation of the products produced by Curaxys.

It also includes the team training management, the documentation of all reports generated during the characterisation process and the monitoring and assessment of the control monitoring and the observation of the GMP standard working procedures.

The ideal candidate will be able to :

  • Manage and control tests required for structural characterisation assays of products produced by Curaxys
  • Experience in mass spectrometry (MALDI, MALDI-TOF, Electrospray MS) in characterisation of proteins :
  • Post-translational modifications
  • Glycosylation pattern
  • Determination of Disulfide brige / Sulfidryl group
  • Scrambled forms
  • Skills in the following molecular and cellular biology techniques :
  • Electrophoresis : SDS-PAGE (1-D, 2-D), Western-Blot
  • Proteins quantification : Bradford, ELISA.
  • Gel documentation and analysis system
  • HPLC; HP-RPC; HP-IEC
  • Protein purification (affinity, ion exchange, size exclusion chromatography) with FPLC
  • Demonstrable leadership skills, ability to manage, supervise and coordinate a department team
  • Working according to GMP standards
  • Maintenance and writing of Standars Operating Procedures
  • Qualifications

    Researchers with a PhD or MSc degree in Chemistry, Biochemistry, Biology, Pharmacy or Chemistry Engineering, with a minimum average qualification of 1.

    7 will be considered suitable candidates. Also, English fluency is a key issue and must be demonstrated.

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