PET Analyst - Neuroimaging Facility
Barcelona Beta Brain Research Center
Barcelona, Spain
hace 3 días
source : Euraxess

About the employer

The Barcelonaβeta Brain Research Center (BBRC) is a research center dedicated to the prevention of Alzheimer's disease and the study of cognitive functions affected in healthy and pathological aging.

It was created in 2012 by the Pasqual Maragall Foundation, with the support of the Pompeu Fabra University.

The mission of the BBRC is to provide innovative solutions to decipher and prevent biological changes and cognitive dysfunction associated with neurodegenerative diseases.

Due to the aging of the world population, these diseases constitute a global challenge, since for example, dementia can reach epidemic levels in 2050, with a forecast of more than 150 million people affected, if is not found a way to prevent its appearance and development.

The BBRC received the HR Excellence in Research award (HRS4R) granted by the European Commission; a recognition that shows its adherence to the principles of the European Charter for Researchers and the Code of Conduct for the Recruitment of Research Staff.

The center offers a stimulating and favorable working environment in accordance with the Charter and Code, which describe the rights and responsibilities of researchers and their employers, and contributes to the creation of a transparent, attractive and open ecosystem at international level.

Pasqual Maragall Foundation, Pompeu Fabra University and la Caixa Foundation are permanent members of the BBRC Board. The center is affiliated and located in the Ciutadella Campus of the Pompeu Fabra University of Barcelona, in a building inaugurated in 2016.

The BBRC headquarters has excellent technical facilities, including a 3TMR scanner dedicated to research, and spaces for conducting Clinical Trials and EEG.

State-of-the-art scientific facilities, effective management and continuous high-standard peer-review evaluation are the BBRC core proceedings to ensure achieving world-class research results.

BBRC is also part of the Barcelona Biomedical Research Park (PRBB), a large research facility that hosts other seven different research institutions related to biomedical research, including the Center for Genomic Regulation (CRG), the Hospital del Mar Medical Research Institute (IMIM), the Department of Experimental and Health Sciences of the Pompeu Fabra University (CEXS-UPF), the Institute of Evolutionary Biology (IBE CSIC-UPF), the Barcelona Institute of Global Health (ISGlobal) and the Barcelona site of the European Molecular Biology Laboratory (EMBL), among others, in a multidisciplinary, collaborative and stimulating international environment in close contact with a clinical setting, thus conducive to translational research.

More information about BBRC :

About the project

The ALFA (for Alzheimer and Families) parent cohort, established by the Barcelonaβeta Brain Research Center, comprises nearly 3.

000 cognitively normal participants, most of whom are first-degree descendants of AD patients. This cohort was established as a research platform to characterize preclinical Alzheimer’s disease (AD) in asymptomatic individuals and will serve to untangle the natural history of the disease and to model the preclinical stages to develop successful trials to prevent AD.

Within the ALFA programme, the ALFA+ cohort study is composed of 420 cognitively unimpaired participants, aged between 45 and 65 years at ALFA baseline visit, who have been thoroughly characterised from a sociodemographic, clinical, lifestyle, cognitive, genetic and biomarker (both fluid and neuroimaging).

Participants are followed every 3 years : so far we have conducted the study’s baseline visit (2016-2019) and the first follow-up visit (2019-2022).

Within ALFA+, PET scans to measure the presence, burden and extent of abnormal amyloid-β and tau pathology are performed.

PET scans with other tracers (e.g. FDG PET) have also been collected or are being considered. These scans are analysed in combination with MRI scans using state-of-the-art quantification pipelines to unlock their full research value

About the job

BBRC is looking for a full-time position as PET Analyst with the mission to perform the longitudinal analysis of PET scans of BBRC studies.

The candidate will work closely with the neuroimaging research group and the neuroinformatics unit.

Main Responsibilities

The responsibilities for this position include :

  • Applying and developing analytical pipelines for amyloid-β and tau PET scans (e.g. Centiloid, Regional Staging Methods, etc )
  • Analyzing and communicating resulting data in the context of the main variables of participants in BBRC studies.
  • Help to draft research manuscripts and presentations
  • We offer

  • Starting date : Immediately.
  • Full-time position, 38hours weekly.
  • Salary will depend on experience and will be in accordance to BBRC’s salary scales.
  • Hybrid working model (on-site + teleworking).
  • The Foundation offers an extended vacation period and the possibility of benefit from flexible working hours.
  • Possible to pursue Scientific career / PhD Thesis.
  • Join a team of highly specialized staff in neuroimaging analysis and MRI physics.
  • We offer and promote a diverse and inclusive environment and welcomes applicants regardless of age, disability, gender, nationality, ethnicity, religion, sexual orientation or gender identity.

    We offer as well, the unique research opportunity in a highly innovative project in a multidisciplinary institution.

    In the BBRC we also care about developing your professional abilities and career. We evaluate the potential of our team in order to develop the skills necessary to achieve a high level of professional performance.

    Application process

    To apply, please submit a single PDF file containing the following :

  • 1) Cover letter describing research interests and relevant background;
  • 2) CV

    3) All files or inquiries should be submitted electronically to :

    Subject : PET Analyst

    We inform you that your personal data will be part of a file which Pasqual Maragall Foundation and Barcelonaβeta Brain Research Center is responsible for, in order to manage the job offer you have requested.

    Once the process is complete, the data processed will be erased.

    You have the right to exercise the rights of access, rectification, cancellation and opposition recognized in Regulation (EU) 2016 / 679 (General Data Protection Regulation), to be addressed to the Pasqual Maragall Foundation and Barcelonaβeta Brain Research Center : Wellington Street 30, 08005 Barcelona.

    Requirements

  • Degree in Physics, Engineering or related field. Holding a PhD will be favorably valued.
  • Strong expertise in the analysis of amyloid and tau PET scans. Knowledge of kinetic modeling of PET data will be favorably valued.
  • Experience with standard MRI analysis suites (SPM, Freesurfer, FSL, etc ).
  • Scripting in Matlab, Python and / or R.
  • Good knowledge of PET physics.
  • Proficient in English.
  • Capacity to work independently and communicate efficiently.
  • It is desirable for the candidate to have experience in drafting research manuscripts and general knowledge of Alzheimer’s disease or other neuropsychiatric diseases.
  • Personal skills

  • Be a team player.
  • Flexibility to act with multidisciplinary teams.
  • Capacity to work independently and communicate efficiently.
  • Should demonstrate integrity values and must possess effective interpersonal skills.
  • Interest in joining a non-profit organization with a mission of high social impact.
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